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Antigenic Specificity | CD207 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 69-328 of human CD207 (NP 056532.4). |
Other Names | [CLEC4K] |
Gene, Accession # | [CD207], Gene ID: 50489, NCBI: NP_056532.4, UniProt: Q9UJ71 |
Catalog # | MBS8546185 |
Price | $280 |
Order / More Info | CD207 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |