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Antigenic Specificity | FOXM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total FOXM1 protein. Forkhead box M1 (FoxM1) is a forkhead box family transcription factor that regulates a number of genes throughout the cell cycle to help control DNA replication, mitosis and cell proliferation. FoxM1 expression increases during G1 and S and reaches maximum levels in G2/M (1-3). Nuclear translocation occurs just before entry into G2/M and is associated with FoxM1 phosphorylation (4). Phosphorylation of FoxM1 by MAPK (Ser331 Ser704), Cyclin/Cdk (Thr600, Thr611, Thr672), Plk1 (Ser715, Ser724), and Chk2 (Ser376) stabilizes and activates FoxM1 (4-7). Forkhead box M1 is expressed in all embryonic tissues but is restricted to proliferating tissues in adults (8). Recent studies have show |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human FOXM1. |
Other Names | [FKHL16; FOXM1B; HFH-11; HFH11; HNF-3] |
Gene, Accession # | [FOXM1], Gene ID: 2305, NCBI: NP_001230017.1, UniProt: Q08050 |
Catalog # | MBS9402305 |
Price | $255 |
Order / More Info | FOXM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |