Edit |   |
---|---|
Antigenic Specificity | CXCR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of o |
Immunogen | Immunogen: A synthetic peptide of human CXCR2 Calculated Molecular Weight: 41kDa |
Other Names | [CD182; IL8R2; IL8RA; IL8RB; CMKAR2; CDw128b], [CXCR2; CXCR2; CD182; IL8R2; IL8RA; IL8RB; CMKAR2; CDw128b; IL8RB; CXC-R2; CXCR-2; IL-8R B] |
Gene, Accession # | [CXCR2], Gene ID: 3579, NCBI: P25025.2, UniProt: P25025 |
Catalog # | MBS127565 |
Price | $200, $275, $430 |
Order / More Info | CXCR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |