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Antigenic Specificity | BACE1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect BACE-1 in human samples. Background: Beta-secretase 1 (BACE1) also known as beta-site APP cleaving enzyme 1 (beta-site amyloid precursor protein cleaving enzyme 1), memapsin-2 (membrane-associated aspartic protease 2), and aspartyl protease 2 (ASP2), beta-Secretase, and is a member of the peptidase A1 protein family, BACE1 is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. BACE1 is an aspartic-acid protease important in the pathogenesis of Alzheimer's disease, and in the formation of myelin sheaths in peripheral nerve cells. The transmembrane protein contains two active site aspartate residues in its extracellular protein domain and may function as a dimer. This |
Immunogen | Immunogen: Recombinant protein beta Secretase 1 (BV-M52). Positive Control: Western blot: Recombinant protein |
Other Names | [ASP2; BACE; HSPC104; KIAA1149; Beta-secretase-1; memapsin-2; aspartyl-protease-2; beta-site-APP-cleaving-enzyme-1], [BACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2; Beta-site APP cleaving enzyme 1] |
Gene, Accession # | [BACE1], Gene ID: 23621, NCBI: NP_001193978.1, UniProt: P56817 |
Catalog # | MBS841389 |
Price | $150, $325 |
Order / More Info | BACE1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |