TrkC Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTrkC
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis TrkC antibody is generated from rabbits immunized with a his tag recombinant protein of human TrkC. TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.
Immunogenn/a
Other Names[NT-3 growth factor receptor; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase; NTRK3; TRKC]
Gene, Accession #[NTRK3], Gene ID: 4916, NCBI: NP_001012338.1, UniProt: Q16288
Catalog #MBS9213506
Price$165, $370
Order / More InfoTrkC Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMcGregor, L.M., et al., Genomics 22(2):267-272 (1994). Shelton, D.L., et al., J. Neurosci. 15 (1 Pt 2), 477-491 (1995).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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