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Antigenic Specificity | Phospho-ERK 1/2 (Y222/205) |
Clone | 4G3 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-ERK 1/2 (Y222/205) protein detects endogenous levels of MAPK1/MAPK3. MAPK1 (mitogen-activated protein kinase 1) encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its |
Immunogen | Immunogen: Synthetic Peptide of Phospho-ERK 1/2 (Y222/205) at AA range of 140-220 |
Other Names | [Mouse Phospho-ERK 1/2 (Y222/205) Mouse (4G3); MAPK1/MAPK3] |
Gene, Accession # | Gene ID: 5595, NCBI: NP_001035145.1, UniProt: P27361 |
Catalog # | MBS9700515 |
Price | $130, $220, $325 |
Order / More Info | Phospho-ERK 1/2 (Y222/205) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |