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Antigenic Specificity | PHO1 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A, also known as APOBEC3A, is a gene of the APOBEC3 family found in humans, non-human primates, and some other mammals.This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22.The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two t |
Immunogen | Immunogen: E Coli-derived human PHO1 recombinant protein (Position: M1-L63). Subcellular Localization: Nucleus. Cytoplasm. Tissue Specificity: Expressed in peripheral leukocytes with higher expression in CD14-positive phagocytic cells. Highly expressed in keratinocytes and in periphery blood monocytes. Also detected in non-lymphoid tissues including lung and adipose tissues. Found at high levels in colorectal adenocarcinoma, Burkitt's lymphoma and chronic myelogenous leukemia. |
Other Names | [DNA dC->dU-editing enzyme APOBEC-3A; A3A; Phorbolin-1; APOBEC3A] |
Gene, Accession # | [PHO1], Gene ID: 100913187, NCBI: NP_001180218.1, UniProt: P31941 |
Catalog # | MBS1750588 |
Price | $280 |
Order / More Info | PHO1 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |