HAP1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HAP1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | HAP1 Antibody: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. HAP1 was initially identified through a two-hybrid library screening; the binding of HAP1 to huntingtin correlated with the expansion of the polyglutamine tract. HAP1 also interacts with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), suggesting that HAP1 may play a role in vesicular trafficking or organelle transport. HAP1 is also involved with the huntingtin-enhanced BDNF transport along the cellular microtubles. Attenuation of this process led to the loss of neurotrophic support and neuronal toxicity, which suggests |
| Immunogen | Immunogen: HAP1 antibody was raised against a 19 amino acid synthetic peptide from near the center of human HAP1. Buffer: HAP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [HAP1; HLP; HAP2; HIP5; hHLP1; HLP1; Huntingtin-associated protein 1; Neuroan 1; HAP-1; huntingtin-associated protein 1], [HAP1; HAP1; HLP; HAP2; HIP5; hHLP1; HAP2; HLP1; HAP-1] |
| Gene, Accession # | [HAP1], Gene ID: 9001, NCBI: CAC09418, UniProt: P54257 |
| Catalog # | MBS150985 |
| Price | $375 |
| Order / More Info | HAP1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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