MPYS Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MPYS |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MPYS Antibody: MPYS is a recently identified plasma membrane tetraspanner that is associated with major histocompatibility complex class II (MHC-II) and mediates its transduction of apoptotic signals. It has also been found to be associated with VISA, a mitochondrial protein that acts as an adaptor in virus-triggered signaling. MPYS also interacts with IRF3 and recruits the kinase TBK1 to the VISA-associated complex, acting as a critical mediator of virus-triggered IRF3 activation and interferon (IFN) expression. It is thought that the binding of nucleic acid to the innate immune protein RIG-I causes complex formation between RIG-I, VISA, and MPYS. This complex then recruits TBK1 to phosphorylate IRF3 which then directly activates IFN trans |
| Immunogen | Immunogen: MPYS antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MPYS. Buffer: MPYS Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [MPYS; ERIS; MITA; MPYS; NET23; STING; ERIS; Stimulator of interferon genes protein; Endoplasmic reticulum interferon stimulator; hSTING; transmembrane protein 173], [TMEM173; TMEM173; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; ERIS; MITA; STING; hSTING; ERIS; hMITA] |
| Gene, Accession # | [TMEM173], Gene ID: 340061, NCBI: NP_938023, UniProt: Q86WV6 |
| Catalog # | MBS150515 |
| Price | $375 |
| Order / More Info | MPYS Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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