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Antigenic Specificity | Caspase 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 200 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects proform and the cleaved large fragment of Caspase-3. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 3 is synthesized as an inactive pro enzyme (32 kDa) that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by another upstream protease. The processed form of Caspase 3 consists of large (17 kD) and small (12 kD) subunits which associate to form an active enzyme. The active Caspase 3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e. g., PARP and DFF). |
Immunogen | Immunogen: Caspase 3 antibody was raised in Rabbit using synthetic peptide corresponding to the C-terminus of caspase-3 large fragment as the immunogen. |
Other Names | [Rabbit Caspase 3; Caspase 3; Caspase 3; Caspase-3; Cysteine-Aspartic Acid Protease 3; Caspase 3; Caspase 3; Caspase-3; Caspase 3; Caspase-3] |
Gene, Accession # | n/a |
Catalog # | MBS5309063 |
Price | $680 |
Order / More Info | Caspase 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |