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Antigenic Specificity | Plectin |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Plectin(PLEC) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Plectin, known as PLEC, is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes. Plectin is expressed as several protein isoforms in a wide range of cell types a |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Plectin (2644-2671aa RFIEQEKAKLEQLFQDEVAKAQQLREEQ), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids. Ig Type: Rabbit IgG |
Other Names | [Plectin; EBS1; EBSO; HD1; Hemidesmosomal protein 1; PCN; pleC; PLEC_HUMAN; PLEC1; PLEC1b; Plectin 1; plectin 1 intermediate filament binding protein 500kDa; Plectin 6; Plectin; Plectin-1; PLTN; plectin], [PLEC; PLEC; HD1; PCN; EBS1; EBSO; PLTN; EBSMD; EBSND; EBSOG; EBSPA; PLEC1; LGMD2Q; PLEC1b; PLEC1; PCN; PLTN; HD1] |
Gene, Accession # | Gene ID: 5339, NCBI: NP_000436.2, UniProt: Q15149 |
Catalog # | MBS177821 |
Price | $315 |
Order / More Info | Plectin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Svitkina TM, Verkhovsky AB, Borisy GG (Nov 1996). Plectin sidearms mediate interaction of intermediate filaments with microtubules and other components of the cytoskeleton. The Journal of Cell Biology135 (4): 991-1007. 2. Wiche G (Sep 1998). Role of plectin in cytoskeleton organization and dynamics(ABSTRACT). Journal of Cell Science. 111 (Pt 17) (17): 2477-86. |