NRG1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNRG1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionHeregulin (HRG), also called neuregulin (NRG1), neu differentiation factor (NDF) or glial growth factor-2 (GGF-2), is a soluble growth factor synthesized as a transmembrane precursor molecule. Metalloproteinases and other proteases catalyze the cleavage of its extracellular domain which is then released and functions as a ligand for ErbB3 and ErbB4 receptor tyrosine kinase. The signaling pathways of HRG-ErbB3/ErbB4 are involved in regulation of cell proliferation, differentiation, invasion, and survival of both normal and malignant tissues (1, 2). Abnormality of HRG-ErbB signaling leads to development of a variety of human diseases.HRG family has four isoforms including HRG-1,-2,-3 and-4, which are derived from alternative exon splicing. Mo
ImmunogenImmunogen: Recombinant protein of human NRG1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[NRG1; ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; NDF; SMDF]
Gene, Accession #[NRG1], Gene ID: 3084, NCBI: NP_001153467.1, UniProt: Q02297
Catalog #MBS8505054
Price$310
Order / More InfoNRG1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Breuleux, M. (2007) Cell Mol Life Sci 64, 2358-77. 2. Ozaki, M. et al. (2004) J Neurochem 91, 176-88. 3. Falls, D.L. (2003) Exp Cell Res 284, 14-30.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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