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Antigenic Specificity | BCL2L11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total BCL2L11 protein. BCL2L11/Bod is a pro-apoptotic protein belonging to the BH3-only group of Bcl-2 family members including Bad, Bid, Bik, Hrk and Noxa that contain a BH3 domain but lack other conserved BH1 or BH2 domains (1,2). BCL2L11 induces apoptosis by binding to and antagonizing anti-apoptotic members of the Bcl-2 family. Interactions have been observed with Bcl-2, Bcl-xL, Mcl-1, Bcl-w, Bfl-1 and BHRF-1 (1,2). BCL2L11 functions in regulating apoptosis associated with thymocyte negative selection and following growth factor withdrawal, during which BCL2L11 expression is elevated (3-6). Three major isoforms of BCL2L11 are generated by alternative splicing: BCL2L11EL, BCL2L11L and BCL2L11S (1) |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human BCL2L11. |
Other Names | [BAM; BIM; BOD; BimL; BimS] |
Gene, Accession # | [BCL2L11], Gene ID: 10018, NCBI: NP_001191035.1, UniProt: O43521 |
Catalog # | MBS9409708 |
Price | $255 |
Order / More Info | BCL2L11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |