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Antigenic Specificity | FAK (Phospho-Ser843) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of FAK only when phosphorylated at serine 843. Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine843(R-G-S(p)-I-D) derived from Human FAK. |
Other Names | [FADK 1; FAK1; Focal adhesion kinase 1; PTK2; pp125FAK] |
Gene, Accession # | [FAK], Gene ID: 5747, NCBI: NP_001186578.1, UniProt: Q05397 |
Catalog # | MBS9403939 |
Price | $200, $255 |
Order / More Info | FAK (Phospho-Ser843) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |