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Antigenic Specificity | SUZ12 |
Clone | [2B12-B4-C0] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. (Provided by RefSeq) SUZ12 is overexpressed in several human tumors, including tumors of the colon, breast and liver.Tissue specificity: Overexpressed in breast and colon cancer. UniPort Summary Function: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3, leading to transcriptional repression of the affected target gen |
Immunogen | Immunogen: Purified recombinant fragment of human SUZ12 expressed in E Coli. Sequence Similarities: Contains 1 C2H2-type zinc finger. |
Other Names | [ChET 9 protein; CHET9; Chromatin precipitated E2F target 9 protein; JJAZ1; Joined to JAZF1 protein; KIAA0160; Polycomb protein SUZ12; Suppressor of zeste 12 homolog; Suppressor of zeste 12 protein homolog; SUZ12; SUZ12 polycomb repressive complex 2 subunit; SUZ12_HUMAN], [CHET9; JJAZ1; KIAA0160; SUZ12] |
Gene, Accession # | [SUZ12], Gene ID: 23512, NCBI: NP_056170.2, UniProt: Q15022 |
Catalog # | MBS476107 |
Price | $335 |
Order / More Info | SUZ12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |