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Antigenic Specificity | BBC3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 2 mg/mL |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Recombinant Human Bcl-2-binding component 3 protein |
Other Names | [BBC 3; Bbc3; BBC3; BCL 2 binding component 3; Bcl-2-binding component 3; BCL2 binding component 3; JFY 1; JFY-1; JFY1; p53 up regulated modulator of apoptosis; p53 up-regulated modulator of apoptosis; p53 Upregulated Modulator of Apoptosis; PUMA alpha; PUMA/JFY1] |
Gene, Accession # | [BBC3], Gene ID: 27113, NCBI: NP_001120712.1, UniProt: Q9BXH1 |
Catalog # | MBS2554128 |
Price | $110, $150, $225 |
Order / More Info | BBC3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |