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Antigenic Specificity | Siglec-5/14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Siglec-5/14 Polyclonal Antibody detects endogenous levels of Siglec-5/14 protein. SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The sialic acid binding Ig like lectin 5 is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Siglec-5/14 |
Other Names | [Rabbit Siglec-5/14; CD33L2; OBBP2; Sialic acid-binding Ig-like lectin 5; Siglec-5; CD33 antigen-like 2; Obesity-binding protein 2; OB-BP2; OB-binding protein 2; CD170; SIGLEC14; Sialic acid-binding Ig-like lectin 14; Siglec-14] |
Gene, Accession # | [SIGLEC5], Gene ID: 8778, NCBI: O15389.1, UniProt: O15389 |
Catalog # | MBS9703659 |
Price | $130, $220, $325 |
Order / More Info | Siglec-5/14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |