TRIO Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRIO
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: TRIO antibody detects endogenous levels of total TRIO. Function: Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases (PubMed:8643598, PubMed:27418539). Involved in coordinating actin remodeling, which is necessary for cell migration and growth (PubMed:10341202). In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses (By similarity). May act as a regulator of adipogenesis (By similarity).Subunit Structure: Interacts with CARMIL1 (PubMed:19846667). Interacts with PTPRF/LAR (PubM
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cytoplasm. Tissue Specificity: Widely expressed, with highest levels in heart, skeletal muscle, and brain. Predicted Cross Reactivity: Pig, Zebrafish, Horse, Rabbit, Dog, Chicken Similarity: Pig (100%), Zebrafish (100%), Horse (100%), Rabbit (100%), Dog (100%), Chicken (100%)
Other Names[ARHGEF23; MEBAS; MRD44; PTPRF-interacting protein; tgat; trio; Trio Rho guanine nucleotide exchange factor; TRIO_HUMAN; Triple functional domain (PTPRF interacting); Triple functional domain protein]
Gene, Accession #[TRIO], Gene ID: 7204, NCBI: NP_009049.2, UniProt: O75962
Catalog #MBS9604199
Price$240, $280
Order / More InfoTRIO Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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