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Antigenic Specificity | TRIO |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TRIO antibody detects endogenous levels of total TRIO. Function: Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases (PubMed:8643598, PubMed:27418539). Involved in coordinating actin remodeling, which is necessary for cell migration and growth (PubMed:10341202). In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses (By similarity). May act as a regulator of adipogenesis (By similarity).Subunit Structure: Interacts with CARMIL1 (PubMed:19846667). Interacts with PTPRF/LAR (PubM |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Tissue Specificity: Widely expressed, with highest levels in heart, skeletal muscle, and brain. Predicted Cross Reactivity: Pig, Zebrafish, Horse, Rabbit, Dog, Chicken Similarity: Pig (100%), Zebrafish (100%), Horse (100%), Rabbit (100%), Dog (100%), Chicken (100%) |
Other Names | [ARHGEF23; MEBAS; MRD44; PTPRF-interacting protein; tgat; trio; Trio Rho guanine nucleotide exchange factor; TRIO_HUMAN; Triple functional domain (PTPRF interacting); Triple functional domain protein] |
Gene, Accession # | [TRIO], Gene ID: 7204, NCBI: NP_009049.2, UniProt: O75962 |
Catalog # | MBS9604199 |
Price | $240, $280 |
Order / More Info | TRIO Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |