CD1a (Mature Langerhans Cells Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD1a (Mature Langerhans Cells Marker)
Clone[SPM120]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionSpecificity: At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic l
ImmunogenImmunogen: Human thymus cells
Other Names[Cortical thymocyte antigen CD1A, Epidermal dendritic cell marker CD1a, FCB6, HTA1, T cell surface antigen T6 / Leu 6, T-Cell Surface Glycoprotein CD1A], [CD1A; CD1A; R4; T6; CD1; FCB6; HTA1; hTa1 thymocyte antigen]
Gene, Accession #[CD1A], Gene ID: 909, NCBI: NP_001307581.1, UniProt: P06126
Catalog #MBS438445
Price$190, $340, $340
Order / More InfoCD1a (Mature Langerhans Cells Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMcNally, AK. et al. 2011. Exp. Mol. Pathol. 91: 673-681. Matsuda, A. et al. 2009. Invest. Ophthalmol. Vis. Sci. 50: 2871-2877. Gulubova, M. et al. 2008. Clin. Exp. Metastasis. 25: 777-785. Cassaday, RD. et al. 2007. Clin. Cancer Res. 13: 540-549.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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