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Antigenic Specificity | SLC22A2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity. |
Immunogen | Immunogen: Recombinant Human Solute carrier family 22 member 2 protein (48-135AA) |
Other Names | [Solute carrier family 22 member 2; Organic cation transporter 2; hOCT2; SLC22A2; OCT2] |
Gene, Accession # | [SLC22A2], Gene ID: 6582, NCBI: NP_003049.2, UniProt: O15244 |
Catalog # | MBS7103163 |
Price | $160, $235 |
Order / More Info | SLC22A2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |