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Antigenic Specificity | Caspase-3 (active/cleaved) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, Gerbil, human, mouse, rat |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apoptosis, or programmed cell death, is a common property of all multicellular organisms. The current dogma of apoptosis suggests that the components of the core cell-death machinery are integral to cells and widely conserved across species. Caspases, a family of cysteinyl aspartate-specific proteases, are integral components of the cell death machinery (reviewed in Siegal, 2006; and Lavrik et al, 2005). They play a central role in the initiation and execution of apoptotic cell death and in inflammation. Caspases are typically divided into 3 major groups, depending on the structure of their prodomain and their function. Group 1: inflammatory caspases (caspases 1, 4, 5, 11, 12, 14). Group II: initiator of apoptosis caspases (caspases 2, 8, 9 |
Immunogen | Immunogen Information: A recombinant catalytically active human caspase-3 protein was used as immunogen for this antibody |
Other Names | [Casp3; Cpp32; Apopain; CPP-32; Cysteine protease CPP32; LICE; Protein Yama; SCA-1; SREBP cleavage activity 1; to Caspase-3 (active/cleaved); Caspase-3 (active/cleaved); Caspase-3 (active/cleaved)], [Casp3; Casp3; CC3; AC-3; Lice; Yama; mldy; CPP32; SCA-1; CASP-3; CPP-32; Caspase-3; A830040C14Rik; Cpp32; CASP-3; CPP-32; SCA-1] |
Gene, Accession # | [Casp3], Gene ID: 12367, NCBI: P70677.1, UniProt: P70677 |
Catalog # | MBS668572 |
Price | $270 |
Order / More Info | Caspase-3 (active/cleaved) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |