Human Choline Acetyltransferase Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Choline Acetyltransferase |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Peptide Affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Acetylcholine (ACh) is a common neurotransmitter for motoneurons, preganglionic autonomic neurons, postganglionic parasympathetic neurons, a variety of brain regions and some emerging neuron-like stem cells. The metabolism of Ach is relatively simple, involving only two enzymes: choline acetyltransferase (ChAT) for synthesis and acetylcholinesterase (AChE) for degradation. Further, acetylcholine has little function in neurons other than neurotransmission and seems to be neuron specific. It seems that only cholinergic neurons have significant amounts of ChAT making anti-choline acetyltransferase a useful specific marker. ChAT is a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer dis |
| Immunogen | Immunogen: Synthetic peptide from the N-terminal to the mid-protein of human Choline O-Acetyltrasferase. Immunogen Species: Human |
| Other Names | [CHAT_Human; Acetyl CoA choline O Acetyltransferase; Choline Acetylase; CLAT_Human; CMS1A; Choline Acetyltransferase : ATTO 655; Rabbit Human Choline Acetyltransferase; Choline Acetyltransferase], [CHAT; CHAT; CMS6; CMS1A; CMS1A2; CHOACTASE; CHOACTase; ChAT; Choline acetylase] |
| Gene, Accession # | [CHAT], Gene ID: 1103, NCBI: NP_001136401.1, UniProt: P28329 |
| Catalog # | MBS807430 |
| Price | $440 |
| Order / More Info | Human Choline Acetyltransferase Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Houser C.R., Crawford G.D., Barber R.P., Salvaterra P.M., Vaughn J.E. (1983) Brain Research. 266(1): 97-119. 2. Karson C.N., Casanova M.F., Kleinman J.E.m Griffin W.S. (1993) Am J Psychiatry. 150: 454-459. 3. Baskins D.S., et al. (1999) Arch Neurol. 56: 1121-1123. |
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