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Antigenic Specificity | Phospho-GSK3 alpha (Ser282) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-GSK3 alpha (Ser282) Antibody detects endogenous levels of GSK3 alpha only when phosphorylated at Ser282. Description: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance |
Immunogen | Immunogen: A synthesized peptide derived from human GSK3 alpha around the phosphorylation site of Ser282. |
Other Names | [DKFZp686D0638; Glycogen synthase kinase 3 alpha; Glycogen synthase kinase-3 alpha; GSK 3 alpha; GSK 3A; GSK-3 alpha; Gsk3a; GSK3A_HUMAN; GSK3alpha; Serine/threonine protein kinase GSK3A] |
Gene, Accession # | [GSK3 alpha], Gene ID: 2931, NCBI: NP_063937.2, UniProt: P49840 |
Catalog # | MBS9610675 |
Price | $225, $280, $340 |
Order / More Info | Phospho-GSK3 alpha (Ser282) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |