PERK, phosphorylated (Thr980) (PKR-like ER Resident Kinase) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PERK, phosphorylated (Thr980) (PKR-like ER Resident Kinase) antibody, protein, ELISA kits.
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| Antigenic Specificity | PERK, phosphorylated (Thr980) (PKR-like ER Resident Kinase) |
| Clone | [7H50] |
| Host Species | Rabbit |
| Reactive Species | rat |
| Isotype | IgG |
| Format | purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EL/EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes endogenous levels of PERK phosphorylated at Thr980 at ~170kD. Species Crossreactivity: rat. PERK, an eIF2 alpha kinase, is a transmembrane protein resident in the endoplasmic reticulum (ER) membrane and couples ER stress signals to translation inhibition. ER stress increases the activity of PERK, which then phosphorylates eIF2 alpha, resulting in reduced translation. PERK-deficient mice have defects in pancreatic beta cells several weeks after birth, suggesting a role for PERK-mediated translational control in protecting secretory cells from ER stress. PERK activation during ER stress correlates with autophosphorylation of its cytoplasmic kinase domain. Phosphorylation of PERK at Thr980 can serve as a marker for its activation st |
| Immunogen | Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Thr980 of mouse PERK, conjugated to KLH. Species Sequence Homology: mouse. |
| Other Names | [-PERK, phosphorylated (Thr980) (PKR-like ER Resident Kinase)], [PEK; PEK; CG2087; DmelCG2087; DmPEK; DpERK; DPERK; EIF2-like; perk; pERK; Perk; PERK; EIF2AK3; DmPEK; PEK; PERK] |
| Gene, Accession # | Gene ID: 40653, NCBI: NP_001262283.1, UniProt: Q9NIV1 |
| Catalog # | MBS601178 |
| Price | $595 |
| Order / More Info | PERK, phosphorylated (Thr980) (PKR-like ER Resident Kinase) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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