IRF3 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | IRF3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Interferon regulatory factors (IRFs) comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection (1). IRFs play an important role in pathogen defense, autoimmunity, lymphocyte development, cell growth, and susceptibility to transformation. The IRF family includes nine members: IRF-1, IRF-2, ISGF3 gamma/p48, IRF-3, IRF-4 (Pip/LSIRF/ICSAT), IRF-5, IRF-6, IRF-7, and IRF-8/ICSBP. All IRF proteins share homology in their amino-terminal DNA-binding domains. IRF family members regulate transcription through interactions with proteins that share similar DNA-binding motifs, such as IFN-stimulated response elements (ISRE), IFN consen |
| Immunogen | Immunogen: Recombinant protein of human IRF3 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [IRF-3; IRF3] |
| Gene, Accession # | [IRF3], Gene ID: 3661, NCBI: NP_001184051.1, UniProt: Q14653 |
| Catalog # | MBS8501564 |
| Price | $310 |
| Order / More Info | IRF3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Taniguchi, T. et al. (2001) Annu Rev Immunol 19, 623-55. 2. Honda, K. and Taniguchi, T. (2006) Nat Rev Immunol 6, 644-58. 3. Hiscott, J. et al. (1999) J Interferon Cytokine Res 19, 1-13. 4. Kim, T.Y. et al. (2003) J Biol Chem 278, 15272-8. 5. Yoneyama, M. et al. (2002) J Interferon Cytokine Res 22, 73-6. 6. Fitzgerald, K.A. et al. (2003) Nat Immunol 4, 491-6. 7. Kopp, E. and Medzhitov, R. (2003) Curr Opin Immunol 15, 396-401. 8. Servant, M.J. et al. (2003) J Biol Chem 278, 9441-7. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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