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Antigenic Specificity | CD56 / NCAM1 (Neuronal Cell Marker) |
Clone | [SPM128] |
Host Species | Mouse |
Reactive Species | human, rat, zebrafish |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas. |
Immunogen | Immunogen: Membrane preparation of a small cell lung carcinoma |
Other Names | [NCAM, Leu-19, NKH1, MSK39, NCAM120, NCAM140, NCAM180, Neural Cell Adhesion Molecule], [NCAM1; NCAM1; CD56; NCAM; MSK39; NCAM; N-CAM-1; NCAM-1] |
Gene, Accession # | [NCAM1], Gene ID: 4684, NCBI: NP_000606.3, UniProt: P13591 |
Catalog # | MBS438122 |
Price | $190, $340, $340 |
Order / More Info | CD56 / NCAM1 (Neuronal Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Hilkens et al., Int J Cancer. 1984 34:197-206. Kibbelaar et al. Eur. J. Cancer 1991 27:431-435 |