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Antigenic Specificity | NHE3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat, mouse |
Isotype | n/a |
Format | alkaline phosphatase (AP) conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects ~84kDa Scientific Background: Sodium-hydrogen exchanger 3 (NHE3; Slc9a3) is an epithelial transport protein that carries out 1:1 exchange of Na and H across the plasma membrane. It is apically located in the proximal tubule of the kidney, the thick ascending limb of the kidney, and in small intestine (1). NHE3 is phosphorylated and regulated by multiple kinases including PKA, SGK1 and CK2. It can be phosphorylated by calyculin A, and dephosphorylated by PP1 catalytic subunit in vitro (2). |
Immunogen | n/a |
Other Names | [Slc9a3], [Slc9a3; Slc9a3; Nhe3; Nhe3; NHE-3] |
Gene, Accession # | Gene ID: 24784, NCBI: NP_036786, UniProt: P26433 |
Catalog # | MBS805065 |
Price | $440 |
Order / More Info | NHE3 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Kim G.H., Ecelbarger C.A., Knepper M.A. and Packer R.K. (1999) J Am Soc Nephrol. 10: 935-942. 2. Dynia D.W., Steinmetz A.G. and Kocinsky H.S. (2010) Am J Physoil Renal Physiol. 298(3): F745-F753. |