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Antigenic Specificity | PDCD1 |
Clone | [4F12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDCD1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PDCD1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PDCD1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases |
Immunogen | Immunogen: Recombinant human PDCD1 (21-167aa) purified from E. coli |
Other Names | [Programmed cell death 1; CD279; PD1; hPD-1; hPD-l;], [PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1] |
Gene, Accession # | [PDCD1], Gene ID: 5133, NCBI: AAH74740 |
Catalog # | MBS200074 |
Price | $240, $315 |
Order / More Info | PDCD1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Freeman GJ, et al., (2000) J Exp Med. 192 (7):1027-34; Latchman Y, et al., (2001) Nat Immunol. 2 (3):261-8; Nishimura H, HonjoT., (2001) Trends Immunol. 22 (5):265-8; Okazaki T, et al., (2001) Proc Natl Acad Sci USA. 98 (24):13866-71 |