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Antigenic Specificity | SETD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.7 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SETD2 protein. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human SET domain containing 2 |
Other Names | [HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP] |
Gene, Accession # | [SETD2], Gene ID: 29072, NCBI: NP_054878.5, UniProt: Q9BYW2 |
Catalog # | MBS9408796 |
Price | $255 |
Order / More Info | SETD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |