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Antigenic Specificity | Phospho-N-WASP (Tyr256) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-N-WASP(Tyr256) Antibody detects endogenous levels of N-WASP only when phosphorylated at Tyr256. Description: Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression. Plays a role in dendrite spine morphogenesis (By similarity).Post Translational Modifications: Phosphorylation at Ser-242, Tyr-256, Ser-484 and Ser-485 enhances actin polymerization activity.Subunit Structure: Binds actin and the Arp2/3 complex. Interacts with CDC42. Binds to SH3 domains o |
Immunogen | Immunogen: A synthesized peptide derived from human N-WASP around the phosphorylation site of Tyr256. |
Other Names | [DKFZp779G0847; MGC48327; N-WASP; Neural Wiskott Aldrich syndrome protein; Neural Wiskott-Aldrich syndrome protein; NWASP; Wasl; WASL_HUMAN; WASPB; Wiskott Aldrich syndrome gene like; Wiskott Aldrich syndrome gene like protein; Wiskott Aldrich syndrome like; WiskottAldrich syndrome like] |
Gene, Accession # | [N-WASP], Gene ID: 8976, NCBI: NP_003932.3, UniProt: O00401 |
Catalog # | MBS9610394 |
Price | $225, $280, $340 |
Order / More Info | Phospho-N-WASP (Tyr256) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |