HSPG2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | HSPG2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (Paraffin-embedded Section) (IHC-P) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Perlecan (PLC) also known as HSPG2, is a protein that in humans is encoded by the HSPG2 gene. It is mapped to 1p36.12. Perlecan is highly conserved across species and the available data indicate that it has evolved from ancient ancestors by gene duplication and exonshuffling. Perlecan is a key component of the vascular extracellular matrix, here it interacts with a variety of other matrix components and helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. Perlecan can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation |
| Immunogen | Immunogen: E.coli-derived human HSPG2 recombinant protein (Position: F524-K701). Human HSPG2 shares 86% amino acid (aa) sequence identity with mouse HSPG2. |
| Other Names | [Basement membrane-specific heparan sulfate proteoglycan core protein; Basement membrane specific heparan sulfate proteoglycan core protein; Endorepellin (domain V region); Heparan Sulfate Proteoglycan; Heparan sulfate proteoglycan of basement membrane; HSPG 2; HSPG; Hspg2; LG3 peptide; Perlecan; PGBM_HUMAN; PLC; Schwartz Jampel syndrome 1 (chondrodystrophic myotonia); SJA; SJS; SJS1; heparan sulfate proteoglycan 2], [HSPG2; HSPG2; PLC; SJA; SJS; HSPG; SJS1; PRCAN; HSPG; PLC] |
| Gene, Accession # | [HSPG2], Gene ID: 3339, NCBI: NP_001278789.1, UniProt: P98160 |
| Catalog # | MBS177806 |
| Price | $315 |
| Order / More Info | HSPG2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Arikawa-Hirasawa E, Le AH, Nishino I, Nonaka I, Ho NC, Francomano CA et al. (May 2002). 2. Iozzo RV (1994). Perlecan: a gem of a proteoglycan. Matrix Biol. 14 (3): 203-8. 3. Kallunki P, Eddy RL, Byers MG, Kestila M, Shows TB, Tryggvason K (October 1991). Cloning of human heparan sulfate proteoglycan core protein, assignment of the gene (HSPG2) to 1p36.1----p35 and identification of a BamHI restriction fragment length polymorphism. Genomics 11 (2): 389-96. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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