Edit |   |
Antigenic Specificity | Human CD16 |
Clone | [4ACB16] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 4ACB16 reacts with human CD16, a 50-65 kDa Fcg receptor IIIa (FcgRIII), expressed on NK cells, monocytes/macrophages and granulocytes. It is a human NK cell associated antigen. CD16 is a low affinity receptor for IgG which functions in phagocytosis and ADCC, as well as in signal transduction and NK cell activation. The CD16 antibody blocks the binding of soluble immune complexes to granulocytes.This clone is cross reactive with non-human primate. |
Immunogen | n/a |
Other Names | [CD16, partial; Low affinity immunoglobulin gamma Fc region receptor III-A; low affinity immunoglobulin gamma Fc region receptor III-A; Fc fragment of IgG receptor IIIa; CD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; CD_antigen: CD16a] |
Gene, Accession # | [CD16], Gene ID: 2214, NCBI: AAB33925.2 |
Catalog # | MBS8501996 |
Price | $280, $300 |
Order / More Info | Human CD16 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Knapp, W., et al. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York. 2.Stroncek, D.F., et al. (1991) Blood 77:1572. 3.Wirthmueller, U., et al. (1992) J. Exp. Med. 175:1381. 4.Barclay, N.A., et al. (1993) The Leucocyte Antigen FactBook, CD16 section, Academic Press Inc., San Diego, Calfornia, p. 136. |