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Antigenic Specificity | Phospho-p70 S6 Kinase beta (Ser423) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-p70 S6 Kinase beta (Ser423) antibody detects endogenous levels of p70 S6 Kinase beta only when phosphorylated at Serine 423. Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B).Function: Phosphorylates specifically ribosomal protein S6.Post-translational Modifications: Phosphorylated and activated by MTOR. Phosphorylation by PKC within the NLS in response to mitogenic stimuli causes cytoplasmic retention.Similarity: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S |
Immunogen | Immunogen: A synthesized peptide derived from human p70 S6 Kinase beta around the phosphorylation site of Serine 423 Subcellular Location: Nucleus Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (91%), Bovine (91%), Horse (82%), Sheep (91%), Dog (91%) |
Other Names | [70 kDa ribosomal protein S6 kinase 2; EC 2.7.11.1; KS6B2_HUMAN; p70 beta; p70 ribosomal S6 kinase beta; p70 S6 kinase beta; p70 S6K-beta; p70 S6KB; p70 S6Kbeta; p70(S6K) beta; p70-beta; p70-S6K 2; P70S6K2; p70S6Kb; Ribosomal protein S6 kinase 70kDa, polypeptide 2; Ribosomal protein S6 kinase beta 2; Ribosomal protein S6 kinase beta-2; Rps6kb2; S6 kinase related kinase; S6 kinase-related kinase; S6K beta 2; S6K beta; S6K-beta; S6K-beta-2; S6K2; Serine/threonine protein kinase 14 beta; Serine/threonine-protein kinase 14B; SRK; STK14B] |
Gene, Accession # | [RPS6KB2], Gene ID: 6199, NCBI: NP_003943.2, UniProt: Q9UBS0 |
Catalog # | MBS9601255 |
Price | $240, $280 |
Order / More Info | Phospho-p70 S6 Kinase beta (Ser423) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |