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Antigenic Specificity | Phospho- JNK/SAPK (pThr183/pTyr185) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse, chicken, bovine dog |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | Size: 100 ug/200 ul |
Applications | ELISA, Western Blot, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human JNK protein. It also reacts with rat and mouse JNK protein. The other species are not tested. c-Jun N-terminal Kinase (JNK) is a Stress Activated Protein Kinase/Map Kinase (SAPK/MAPK). There are three isoforms, JNK1 (~49 kDa), JNK2 (~55 kDa), and JNK3 (~54 kDa). JNK is dually phosphorylated at Thr 183 and Tyr 185 by protein kinases MKK4 and MKK7. The JNK and p38 pathways function to modulate cell-cycle, apoptotic and transcriptional responses to stress. |
Immunogen | Antigen Preparation: A synthetic peptide surrounding to the epitope -TPY- with dual phosphorylation sites at Thr183 and Tyr185 of human JNK/SAPK. |
Other Names | n/a |
Gene, Accession # | [JNK/SAPK1 (pT183/pY185)] |
Catalog # | MBS462109 |
Price | $285 |
Order / More Info | Phospho- JNK/SAPK (pThr183/pTyr185) Antibody from MYBIOSOURCE INC. |
Product Specific References | Yogev,O., et al. DNA damage-dependent translocation of B23 and p19 ARF is regulated by the Jun N-terminal kinase pathway. Cancer Res. 68 (5), 1398-1406 (2008) |