Edit |   |
---|---|
Antigenic Specificity | GluN2B/NR2B |
Clone | [S59-20] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Antibody Microarray (AM) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~166 kDa. No cross-reactivity against NR2A. NR2B/GluN2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation (1). Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain; NR2B may be a probable target for anti-nociceptive drugs, and may also be useful as analgesics (2). |
Immunogen | Immunogen: Fusion protein amino acids 20-271 (N-terminus) of rat NR2B |
Other Names | [Mouse Rat GluN2B/NR2B IgG2a; GluN2B/NR2B : APC/Cy7; NMDAR2B; hNR3; MGC142180; glutamate receptor subunit epsilon-2; NR3; GluN2B; hNR3; MRD6; NMDAR2B; NR2B; NMDAR2B NMDA] |
Gene, Accession # | [GluN2B/NR2B], Gene ID: 24410, NCBI: NP_036706.1, UniProt: Q00960 |
Catalog # | MBS8002944 |
Price | $510 |
Order / More Info | GluN2B/NR2B Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Zhuo M. (2009) Mol Brain. 2(1): 4. 2. Gurwitz D, and Weizman A. (2002) Drug Discovery Today, 7(7): 403-406. |