CTCF Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCTCF
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
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DescriptionTranscriptional insulators are DNA elements that set boundaries on the actions of enhancer and silencer elements and thereby organize the eukaryotic genome into regulatory domains. All vertebrate insulators appear to use the versatile CTCF protein. CTCF uses various combinations of its 11 zinc fingers to recognize a variety of unrelated DNA sequences. Once bound to DNA, CTCF can function as a transcriptional insulator, repressor, or activator, depending on the context of the binding site [PMID:12787766,15454938]. In vertebrates, this 11 zinc-finger protein is shown to be crucial in processes of epigenetic imprinting, X chromosome inactivation, and associated with various complex human diseases including cancer and diabetes [PMID:23139640].
ImmunogenImmunogen: Recombinant Protein
Other Names[CTCF], [CTCF; CTCF; MRD21]
Gene, Accession #[CTCF], Gene ID: 10664, NCBI: P49711.1, UniProt: P49711
Catalog #MBS125934
Price$275, $430
Order / More InfoCTCF Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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