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Antigenic Specificity | PSD95 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Disks large homolog 4(DLG4) detection. Tested with WB, IHC-P in Human;Rat. Background: DLG4 discs large homolog 4, also known as PSD95 or SAP-90, is a protein that in humans is encoded by the DLG4 gene. It is a member of the membrane-associated guanylate kinase (MAGUK) family. This gene is mapped to 17p13.1. DLG4 can heteromultimerize with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Overexpression of DLG4 in hippocampal neurons could drive maturation of glutamatergic synap |
Immunogen | Immunogen: E Coli-derived human PSD95 recombinant protein (Position: H581-L724). Human PSD95 shares 100% amino acid (aa) sequence identity with both mouse and rat PSD95. Ig Type: Rabbit IgG |
Other Names | [Disks large homolog 4; Discs large homolog 4; Disks large homolog 4; DLG 4; DLG4; DLG4_HUMAN; FLJ97752; FLJ98574; Human post synaptic density protein 95; Human post-synaptic density protein 95; Post synaptic density protein 95; Postsynaptic density protein 95; PSD 95; PSD-95; PSD95; SAP 90; SAP-90; SAP90; Synapse associated protein 90; Synapse-associated protein 90; Tax interaction protein 15; discs, large homolog 4 (Drosophila)], [DLG4; DLG4; PSD95; SAP90; SAP-90; PSD95; PSD-95; SAP-90; SAP90] |
Gene, Accession # | [PSD95], Gene ID: 1742, NCBI: NP_001122299.1, UniProt: P78352 |
Catalog # | MBS178097 |
Price | $315 |
Order / More Info | PSD95 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: DLG4 discs, large homolog 4 (Drosophila). 2. Colledge, M., Snyder, E. M., Crozier, R. A., Soderling, J. A., Jin, Y., Langeberg, L. K., Lu, H., Bear, M. F., Scott, J. D. Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron 40: 595-607, 2003. 3. El-Husseini, A. E.-D., Schnell, E., Chetkovich, D. M., Nicoll, R. A., Bredt, D. S. PSD-95 involvement in maturation of excitatory synapses. Science 290: 1364-1368, 2000. |