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Antigenic Specificity | SNX1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:19816406, Pub |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human SNX1 (NP 003090.2). |
Other Names | [VPS5; HsT17379] |
Gene, Accession # | [SNX1], Gene ID: 6642, NCBI: NP_001229862.1, UniProt: Q13596 |
Catalog # | MBS8547541 |
Price | $280 |
Order / More Info | SNX1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |