Edit |   |
---|---|
Antigenic Specificity | LAMP1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, cow, porcine, mouse, rat and other mammals |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | n/a |
Immunogen | Immunogen: As the name suggests, LAMP1 is a protein primarily associated with the lysosomal membrane. Antibodies to LAMP1 are therefore excellent markers of lysosomes in mammalian cells, though some LAMP1 may also be seen on late endosomes and on the plasma membrane. In a typical cell LAMP1 is associated with spherical vesicles located next to the nucleus and the microtubule organizing center (1). The protein is also known as CD107a, lysosomal associated membrane glycoprotein 1, LGP120 and LAMPA |
Other Names | n/a |
Gene, Accession # | [LAMP1] |
Catalog # | MBS415068 |
Price | $370 |
Order / More Info | LAMP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Matteoni, R. and Kreiss, T. E. Translocation and clustering of endosomes and lysosomes depends on microtubules. J. Cell Biol. 105:1253-1265 (1987).2. Howe CL, Granger BL, Hull M, Green SA, Gabel CA, Helenius A, Mellman I. Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): identification of a highly conserved family of lysosomal membrane glycoproteins. Proc Natl Acad Sci U S A. 85:7577-81 (1988).3. Rohrer J, Schweizer A, Russell D, Kornfeld S. The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane. J Cell Biol. 132:565-76 (1996). |