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Antigenic Specificity | TrkA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) / Immunoprecipitation (IP) (predicted) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects ~140 kDa TrkA. It does not cross-react with TrkB or TrkC. Background: TrkA, the high affinity Nerve Growth Factor (NGF) receptor, autophosphorylates on tyrosine to activate multiple effectors. Phosphorylation at Tyr490 is required for Shc association and activation of the Ras-MAP kinase cascade. Residues Tyr674/675 lie within the catalytic domain, and phosphorylation at these sites reflects Trk kinase activity. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 494 of human TrkA |
Other Names | [Trk-A; TRK1; NTRK1; TRK; CIPA], [NTRK1; NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; MTC; TRK; TRKA; Trk-A] |
Gene, Accession # | [TrkA], Gene ID: 4914, NCBI: BAA34355 |
Catalog # | MBS840182 |
Price | $150, $290 |
Order / More Info | TrkA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |