Crry, Rat Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Crry, Rat antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Crry, Rat |
| Clone | TLD-1C11 |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | F, Flow Cytometry (FC/FACS), FS, Immunofluorescence (IF), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody TLD-1C11 reacts with rat-complement regulator Crry. Complement comprises a system of soluble serum proteins that, upon activiation by antibody (classical pathway), sugars (lectin pathway), or bacterial and foreign surfaces (alternative pathway), directly causes cell damage. Complement is constantly activated at low levels in serum, requiring cells to be protect themselves from damage. In human, cells are protected from complement-mediated damage by expression of membrane-bound complement regulatory proteins, which act at serveral points along the cascade. Human cells are protected by decay-accelerating factor (DAF, CD55), membrane cofactor protein (MCP, CD46) and membrane attack complex inhibitor |
| Immunogen | Immunogen: rat microglial cells |
| Other Names | n/a |
| Gene, Accession # | [Crry] |
| Catalog # | MBS584177 |
| Price | $640 |
| Order / More Info | Crry, Rat Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Flaris, N et al; Characterization of microglia and macrophages in the central nervous system of rats: definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction. Glia 1993, 7: 34 2. McGrath, Y et al; Development of adenovirus vectors encoding rat complement regulators for use in therapy in rodent models of inflammatory diseases. J Immunol 1999, 163: 6834 3. Fraser, D et al; Bacterial expression and membrane targeting of the rat complement regulator Crry: a new model anticomplement therapeutic. Protein Sci 2002, 11: 2512 4. Hanna, S et al; Rat T cells express neither CD55 nor CD59 and are dependent on Crry for protection from homologous complement. Eur J Immunol 2002, 32: 502 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies