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Antigenic Specificity | Rat CD95 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. is a prototype death receptor characterized by the presence of an 80 amino acid death domain in its cytoplasmic tail. This domain is essential for the recruitment of a number of signaling components upon activation by either agonistic anti-CD95 antibodies or cognate CD95 ligand that initiate apoptosis. The complex of proteins that forms upon triggering of CD95 is called the death-inducting signaling complex (DISC). The DISC consists of an adaptor protein and initiator caspases and is essential for induction of apoptosis. CD95 is also crucial for the negative selectio |
Immunogen | Immunogen: Recombinant Rat FAS/TNFRSF6/CD95 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [CD95 antigen, partial; CD95 antigen; tumor necrosis factor receptor superfamily member 6; Fas cell surface death receptor; CD95 antigen] |
Gene, Accession # | [CD95 ], Gene ID: 355, UniProt: Q9UEL0 |
Catalog # | MBS2544706 |
Price | $215, $330, $500 |
Order / More Info | Rat CD95 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |