Mouse CD80 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD80 |
| Clone | [MAB0713] |
| Host Species | Armenian Hamster |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | B7-1 (CD80) and B7-2, together with their receptors CD28 and CTLA4, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. Although both CTLA4 and CD28 can bind to the same ligands, CTLA4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the downregulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. Additionally, B7-2 is expressed at low levels on monocytes and can be upregulated through interferon gamma. B7-1 and B7-2 are both members of the Immunog |
| Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a Armenian Hamster immunized with recombinant Mouse CD80 protein. IgG fraction of the culture supernatant was purified by Protein G affinity chromatography. Reconstitution buffer: PBS(sterile). Antigen: Recombinant Mouse CD80 protein |
| Other Names | [Cd80; B71; Ly53; TSA1; Cd28l; Ly-53; MIC17], [Cd80; Cd80; B71; Ly53; TSA1; Cd28l; Ly-53; MIC17; B7; B7] |
| Gene, Accession # | [CD80], Gene ID: 12519, NCBI: NP_033985.3, UniProt: Q00609 |
| Catalog # | MBS690572 |
| Price | $490 |
| Order / More Info | Mouse CD80 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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