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Antigenic Specificity | Clock (dClock) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Drosophila |
Isotype | n/a |
Format | serum |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes Drosophila Clock. Drosophila sequence has no significant sequence homology with mammalian Clock or Per proteins. CLOCK, a basic helix-loop-helix (bHLH)/PAS protein, is an important factor in the molecular clock mechanism. Mutations in this protein lead to abnormal circadian behavior and defective transcriptional activity. CLOCK has been shown to interact strongly with other bHLH-PAS proteins such as MOP3, a BMAL1 isoform. Several endogenous factors have been linked to rhythmicity or circadian behavior of living organisms. In Drosophila, the genes period (dPer) and timeless (tim), and in Neurospora frequency (frq), have been proposed to be responsible for their circadian rhythm. Recently human and mouse genes encoding a basic heli |
Immunogen | Immunogen: Synthetic peptide corresponding to 17aa within the C-terminus of Drosophila Clock conjugated to KLH. |
Other Names | [Clock (dClock)], [CLOCK; CLOCK; KAT13D; bHLHe8; KIAA0334; BHLHE8; KIAA0334] |
Gene, Accession # | [Clock], Gene ID: 9575, UniProt: O15516 |
Catalog # | MBS610475 |
Price | $720 |
Order / More Info | Clock (dClock) Antibody from MYBIOSOURCE INC. |
Product Specific References | • (1.)Bae K et al (1998) Mol Cell Biol. 18, 6142-6151; Allada R et al (1998) Cell 93, 791-804; Darlington TK et al (1998) Science 280, 1599-1603 |