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Antigenic Specificity | BRCA1 (N-TERMINAL) |
Clone | [BR64] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human BRCA1 antibody, clone BR64 recognizes an epitope within the100 amino acid N-Terminal (NT) regionof human BRCA1, otherwise known as breast cancer type 1 susceptibility protein, a tumor suppressor gene and major player in DNA damage repair, predominantly expressed in the nucleus during the S/G2 phase of the cell cycle.Along with BRCA2, BRCA1 is a high risk gene which is associated with hereditary breast and ovarian cancers, particularly at a younger age of diagnosis. Women carrying the BRCA1 mutation have a 50-95% chance of developing breast cancer in later life, but genetic screening and increased awareness of preventative surgery, can reduce this risk significantly. Deleterious BRCA1 mutations may also increase the risk of |
Immunogen | n/a |
Other Names | [BRCA1; Breast cancer type 1 susceptibility protein; breast cancer type 1 susceptibility protein; BRCA1/BRCA2-containing complex, subunit 1; Fanconi anemia, complementation group S; RING finger protein 53; breast and ovarian cancer susceptibility protein 1; breast and ovarian cancer sususceptibility protein 1; protein phosphatase 1, regulatory subunit 53; breast cancer 1, early onset; RING finger protein 53], [BRCA1; BRCA1; IRIS; PSCP; BRCAI; BRCC1; FANCS; PNCA4; RNF53; BROVCA1; PPP1R53; RNF53] |
Gene, Accession # | [BRCA1], Gene ID: 672, NCBI: AAC37594.1 |
Catalog # | MBS219921 |
Price | $430 |
Order / More Info | BRCA1 (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |