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Antigenic Specificity | Human HLA ABC |
Clone | [YTH862.2] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.2 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Functional Assays (FN)*, Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Human HLA ABC antibody, clone YTH862.2 recognizes a monomorphic determinant on the human HLA Class I heavy chain. Epitope analysis has shown that this antibody binds in the alpha1 domain. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells. Rat anti Human HLA ABC antibody, clone YTH862.2 may be able to induce apoptosis in activated but not resting T cells (Genestier et al. 1997). |
Immunogen | Immunogen: PHA activated human peripheral blood lymphocytes. Fusion Partners: Spleen cells from immunised DA rats were fused with cells of the rat Y3 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | n/a |
Gene, Accession # | [HLA ABC] |
Catalog # | MBS213039 |
Price | $430 |
Order / More Info | Human HLA ABC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |