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Antigenic Specificity | NRG1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.96 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total NRG1 protein. Neuregulin 1 (NRG1) was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specifically expressed and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like d |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 211 of NRG1. |
Other Names | [ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; NDF; SMDF; NRG1; MSTP131; glial growth factor; sensory and motor neuron derived factor anti] |
Gene, Accession # | [NRG1], Gene ID: 3084, NCBI: NP_001153467.1, UniProt: Q02297 |
Catalog # | MBS9403366 |
Price | $320 |
Order / More Info | NRG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |