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Antigenic Specificity | PHAP III |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PHAP III has no cross-reaction to PHAP I and PHAP I2a. Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stim |
Immunogen | Immunogen Type: Peptide Immunogen Description: PHAP III antibody was raised with a synthetic peptide corresponding to amino acids close to carboxy terminus of human PHAP III. |
Other Names | [acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1; Acidic leucine-rich nuclear phosphoprotein 32 family member E; acidic leucine-rich nuclear phosphoprotein 32 family member E; acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; LANP-like protein; LANP-L] |
Gene, Accession # | [PHAP III], Gene ID: 81611, NCBI: NP_112182 |
Catalog # | MBS9414557 |
Price | $320 |
Order / More Info | PHAP III Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |