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Antigenic Specificity | CD1a/HTA1 (Mature Langerhans Cells Marker) |
Clone | [C1A/3249] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic l |
Immunogen | Immunogen: Recombinant fragment (around aa43-173) of human CD1A protein (exact sequence is proprietary) |
Other Names | [Cortical thymocyte antigen CD1A; Epidermal dendritic cell marker CD1a; FCB6; HTA1; T cell surface antigen T6/Leu 6; T-Cell Surface Glycoprotein CD1A] |
Gene, Accession # | [CD1A], Gene ID: 909, NCBI: P06126.4, UniProt: P06126 |
Catalog # | MBS4381375 |
Price | $190, $340, $340 |
Order / More Info | CD1a/HTA1 (Mature Langerhans Cells Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Matsuda, A. et al. 2009. Invest. Ophthalmol. Vis. Sci. 50: 2871-2877. 2. McNally, AK. et al. 2011. Exp. Mol. Pathol. 91: 673-681. |