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Antigenic Specificity | NALP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NALP2 Antibody: NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1β-processing activity and is thought to function as a modulator of NF-κB and procaspase-1 activation in macrophages. It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs). At least two alternatively sp |
Immunogen | Immunogen: NALP2 antibody was raised against a peptide corresponding to 12 amino acids near the carboxy terminus of human NALP2. Buffer: NALP2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [NALP2; NBS1; PAN1; NALP2; PYPAF2; CLR19.9; NBS1; NACHT; LRR and PYD domains-containing protein 2; Nucleotide-binding site protein 1; NLR family, pyrin domain containing 2], [NLRP2; NLRP2; NBS1; PAN1; NALP2; PYPAF2; CLR19.9; NALP2; NBS1; PAN1; PYPAF2] |
Gene, Accession # | [NLRP2], Gene ID: 55655, NCBI: NP_060322, UniProt: Q9NX02 |
Catalog # | MBS150327 |
Price | $375 |
Order / More Info | NALP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |